Inspired by
the structure and interactions of natural nucleobases, presenting: fluorescent nucleobase analogues.
2CNqA
An analogue for Adenine
tCOTP
An analogue for Cytosine
Selected publications
Baladi, T., Nilsson R.J.,
Gallud, A. et al. Stealth fluorescence labeling for live microscopy imaging of mRNA delivery. Journal of the American Chemical Society (2021) 143 (14), 5413-5424 https://doi.org/10.1021/jacs.1c00014
Nilsson, R.J., Baladi, T., Gallud, A. et al.Fluorescent base analogues in gapmers enable stealth labeling of antisense oligonucleotide therapeutics. Sci Rep (2021) 11, 11365. https://doi.org/10.1038/s41598-021-90629-1
Wypijewska del Nogal, A., Füchtbauer, A.F., Bood, M. et al. Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donorNucleic Acids Research (2020) 48 (14): 7640-7652
Füchtbauer, A.F., Preus, S., Börjesson, K. et al.Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations. Sci Rep (2017) 7 (1), 2393. https://doi.org/10.1038/s41598-017-02453-1
Bood, M., Füchtbauer, A.F., Wranne A.M. et al.Pentacyclic Adenine: A Versatile and Exceptionally Bright Fluorescent DNA Base Analog, Chem. Sci., (2018) 9 3494-3502 https://doi.org/10.1039/C7SC05448C
