Fluorescent Nucleobase Analogues

Inspired by the structure and interactions of natural nucleobases, presenting: fluorescent nucleobase analogues.


An analogue for Adenine


An analogue for Cytosine

Selected publications

  1. Baladi, T., Nilsson R.J., Gallud, A. et al. Stealth fluorescence labeling for live microscopy imaging of mRNA delivery. Journal of the American Chemical Society (2021) 143 (14), 5413-5424
  2. Nilsson, R.J., Baladi, T., Gallud, A. et al. Fluorescent base analogues in gapmers enable stealth labeling of antisense oligonucleotide therapeutics. Sci Rep (2021) 11, 11365.
  3. Wypijewska del Nogal, A., Füchtbauer, A.F., Bood, M. et al. Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor Nucleic Acids Research (2020) 48 (14): 7640-7652
  4. Füchtbauer, A.F., Preus, S., Börjesson, K. et al. Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations. Sci Rep (2017) 7 (1), 2393.
  5. Bood, M., Füchtbauer, A.F., Wranne A.M. et al. Pentacyclic Adenine: A Versatile and Exceptionally Bright Fluorescent DNA Base Analog, Chem. Sci., (2018) 9  3494-3502